Saturday - Sunday

Saturday:

In addition to this being the last Saturday of Summer Streets, where Park Avenue and the Avenues that lead to Park from the Brooklyn Bridge are closed - (click this post for info) - -Oops, sorry I forgot to input the link.

6th Avenue will be closed above 42nd Street for a regular crappy street fair.

Also there will be a run in Harlem, maybe a walk to, here are those details:

NYC Health Walk-A-Thon Route: Start on Edgecombe Avenue between 135th Street and 136th Street head north along Edgecombe Avenue at 141st Street bear right (north) onto Bradhurst Avenue proceed north on Bradhurst alongside Jackie Robinson Park turn around at 1-mile mark near intersection of 155th Street to proceed south on Bradhurst alongside Jackie Robinson Park at 143rd Street continue south on Edgecombe Avenue turn right (west) on 135th Street and an immediate right (north) on St. Nicholas Avenue

Finish: On St. Nicholas Avenue near 135th Street alongside St. Nicholas Park

Percy Sutton Harlem 5K Run Start on Edgecombe Avenue between 135th Street and 136th Street head north along Edgecombe Avenue; at 141st Street bear right onto Bradhurst Avenue; turn left (west) at 145th Street; turn right (north) back onto Edgecombe Avenue; 1-mile mark just before 155th Street at 155th Street, take sharp left (south) onto St. Nicholas Place turn right (west) on 150th Street; turn left (south) onto Convent Avenue turn left (east) onto St. Nicholas Terrace; 2-mile mark just after this turn.
Proceed straight (south) along top of St. Nicholas Park; turn left (east) on 127th Street; turn left (north) on St. Nicholas Avenue; proceed straight (north) on St. Nicholas Avenue alongside St. Nicholas Park; 3-mile mark around 134th Street
Finish near 135th Street and St. Nicholas Avenue
The above streets will be closed Saturday from 6am to 4pm for the NYC Health Walk-A-Thon and Percy Sutton 5K Run as permitted by the Mayor's Street Activity Permit Office (SAPO).

Sunday:

These Closures:

3rd Avenue between East 23rd Street and East 34th Street: This street will be closed Sunday from 11am to 6pm for the Church of the Good Shepherd Street Fair as permitted by the Mayor's Street Activity Permit Office (SAPO).

Madison Avenue between East 42nd Street and East 57th Street: This street will be closed Sunday from 11am to 6pm for the Daytop Village Street Festival as permitted by the Mayor's Street Activity Permit Office (SAPO).

And Stanton between Allen and Orchard, will be closed this Sunday as well as a few up coming ones.

This info was gathered from the DOT, and if you want more information on streets and bridges I haven't mentioned, go there.

Also as usual, the Holland tunnel will be closed to outbound traffic from 1am to 8am, both saturday and sunday mornings. check the P.A. for more information on the tunnels, airports, etc..